· Framework/ Head to head

Agno vs DSPy

Both are open source framework options with comparable terms, so the choice comes down to which model of the problem you prefer — compare the descriptions below rather than the licence.

Agno

Fast, lightweight multi-agent runtime with built-in memory and knowledge.

Open source · can be self-hosted · SDKs for Python

DSPy

Programs, not prompts — compile and optimise the prompt against a metric.

Open source · can be self-hosted · SDKs for Python

· Side by side/ 1 of 6 differ
AgnoDSPy
LicenceOpen sourceOpen source
Pricingopen sourceopen source
Self-hostableYesYes
LanguagesPythonPython
Installpip install agnopip install dspy
Keys requiredNoneNone
· Common questions/ FAQ

What is the difference between Agno and DSPy?

Both are open source framework options with comparable terms, so the choice comes down to which model of the problem you prefer — compare the descriptions below rather than the licence. Agno: Fast, lightweight multi-agent runtime with built-in memory and knowledge. DSPy: Programs, not prompts — compile and optimise the prompt against a metric.

Can Agno and DSPy be self-hosted?

Agno can run on your own infrastructure. DSPy can run on your own infrastructure.

Are Agno and DSPy open source?

Agno is open source (open source). DSPy is open source (open source).

Build a stack with AgnoAll framework options
· For agents/ This page, machine-readable

Every page here answers to Accept: text/markdown and returns the same content at roughly a tenth the tokens. No separate site, no toggle — same URL.

curl -s -H "Accept: text/markdown" https://newagent.build/compare/agno-vs-dspy