· Framework/ Head to head

Agno vs LlamaIndex

Both sit in the framework layer with similar commercial terms, so the practical split is language: Agno targets Python and LlamaIndex targets Python.

Agno

Fast, lightweight multi-agent runtime with built-in memory and knowledge.

Open source · can be self-hosted · SDKs for Python

LlamaIndex

Data-first framework — ingestion, indexing and RAG-heavy agents.

Open source · freemium · can be self-hosted · SDKs for Python and TypeScript

· Side by side/ 3 of 6 differ
AgnoLlamaIndex
LicenceOpen sourceOpen source
Pricingopen sourcefreemium
Self-hostableYesYes
LanguagesPythonPython, TypeScript
Installpip install agnopip install llama-index
Keys requiredNoneNone
· Common questions/ FAQ

What is the difference between Agno and LlamaIndex?

Both sit in the framework layer with similar commercial terms, so the practical split is language: Agno targets Python and LlamaIndex targets Python. Agno: Fast, lightweight multi-agent runtime with built-in memory and knowledge. LlamaIndex: Data-first framework — ingestion, indexing and RAG-heavy agents.

Can Agno and LlamaIndex be self-hosted?

Agno can run on your own infrastructure. LlamaIndex can run on your own infrastructure.

Are Agno and LlamaIndex open source?

Agno is open source (open source). LlamaIndex is open source (freemium).

Build a stack with AgnoAll framework options
· For agents/ This page, machine-readable

Every page here answers to Accept: text/markdown and returns the same content at roughly a tenth the tokens. No separate site, no toggle — same URL.

curl -s -H "Accept: text/markdown" https://newagent.build/compare/agno-vs-llamaindex