Both sit in the framework layer with similar commercial terms, so the practical split is language: Mastra targets TypeScript and Agno targets Python.
TypeScript agent framework with workflows, memory, evals and a local playground.
Fast, lightweight multi-agent runtime with built-in memory and knowledge.
| Mastra | Agno | |
|---|---|---|
| Licence | Open source | Open source |
| Pricing | open source | open source |
| Self-hostable | Yes | Yes |
| Languages | TypeScript | Python |
| Install | npm install @mastra/core | pip install agno |
| Keys required | None | None |
Both sit in the framework layer with similar commercial terms, so the practical split is language: Mastra targets TypeScript and Agno targets Python. Mastra: TypeScript agent framework with workflows, memory, evals and a local playground. Agno: Fast, lightweight multi-agent runtime with built-in memory and knowledge.
Mastra can run on your own infrastructure. Agno can run on your own infrastructure.
Mastra is open source (open source). Agno is open source (open source).
Every page here answers to Accept: text/markdown and returns the same content at roughly a tenth the tokens. No separate site, no toggle — same URL.
curl -s -H "Accept: text/markdown" https://newagent.build/compare/mastra-vs-agno